![]() ![]() Well-differentiated and low-grade cancers tend to be slower growing and less likely to spread to other part of the body compared with high-grade or poorly-differentiated adenocarcinomas. They can also be categorized by their differentiation (meaning how closely they resemble a normal cell). Adenocarcinomas are usually graded based on their microscopic appearance as either low-, moderate – or high-grade tumors. They are also frequently mucin-producing cells and can result in accumulated mucin or PMP in the abdomen, but may also spread to other parts of the body, other organs in the abdomen or to the local lymph nodes. Adenocarcinomas are cancerous tumors created by gland-forming cells that line the inside of the appendix.The build-up of mucin (also known as pseudomyxoma peritonei or PMP) can eventually lead to abdominal pain, bloating, and/or bowel obstructions. However, due to the flimsy nature of the appendix wall, if the appendix ruptures or the tumor grows through the wall, neoplastic cells may spread in the abdominal cavity, because the tumors are created by mucin-producing cells that line the inside of the appendix, and a mucinous substance (a gelatinous material) may accumulate in the abdomen. ![]() ![]() This means that they do not have any potential to spread to lymph nodes or through the blood stream to other organs. Low grade mucinous neoplasms of the appendix (formerly known as mucinous cystadenomas) are non-cancerous tumors of the appendix. ![]()
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